Monograph Details
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Urogenital System
> Urinary tract disorders
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PROSED/DS |
| Manufacturer |
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Allergan |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Urinary tract analgesic/antispasmodic/antiseptic. |
| Generic Name |
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Methenamine 81.6mg, phenyl salicylate 36.2mg, methylene blue 10.8mg, benzoic acid 9mg, atropine sulfate 0.06mg, hyoscyamine sulfate 0.06mg; tabs. |
| Also |
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• PROSED EC
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| Indications |
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Relief of lower urinary tract discomfort due to hypermotility. Treatment of formaldehyde-susceptible cystitis, urethritis, trigonitis. |
| Children |
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Not recommended. |
| Adults |
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1 tab 4 times daily. |
| Contraindications |
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Glaucoma. GI or GU obstruction. Cardiospasm. |
| Precautions |
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Maintain acid urine and adequate hydration. Cardiovascular disease. Gastric ulcer. Discontinue if dizziness, tachycardia, or blurred vision occurs. Discolors urine/feces. Elderly. Pregnancy (Cat.C). Nursing mothers. |
| Interactions |
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Allow at least 2 hours after ketoconazole. May be potentiated by antimuscarinics, antimyasthenics, MAOIs, opioids. May be antagonized by thiazide diuretics, urinary alkalinizers. Separate dosing of antacids, antidiarrheals by 1 hour. May reduce absorption of other drugs. Sulfonamides precipitate with formaldehyde in urine; avoid concomitant use. Interferes with colorimetric urine tests. |
| Adverse Reactions |
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Anticholinergic effects (eg, tachycardia, flushing, blurred vision, dizziness, shortness of breath, difficulty in micturition, acute urinary retention, dry mouth). |
| How Supplied |
DS tabs—100
EC tabs—90 |
| Additional Resources |
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• Related Prescribing Note |
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