Monograph Details
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Urogenital System
> Overactive bladder/enuresis
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OXYTROL |
| Manufacturer |
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Watson Pharmaceuticals, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Antispasmodic/anticholinergic. |
| Generic Name |
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Oxybutynin 3.9mg/day; transdermal patch. |
| Indications |
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Overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency. |
| Children |
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Not recommended. |
| Adults |
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Apply to clean, dry area on the abdomen, hip, or buttock. 1 patch twice weekly (every 3–4 days). Rotate application sites. |
| Contraindications |
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Urinary or gastric retention, uncontrolled narrow-angle glaucoma; or patients at risk for these. |
| Precautions |
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Bladder outflow or GI obstruction. Hepatic or renal impairment. Ulcerative colitis. Intestinal atony. Myasthenia gravis. Exposure to high environmental temperature. Pregnancy (Cat.B). Nursing mothers. |
| Interactions |
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CNS depression potentiated by alcohol, other CNS depressants. Additive effects with other anticholinergics. May affect GI absorption of other drugs. Caution with drugs that cause or exacerbate esophagitis (eg, bisphosphonates). |
| Adverse Reactions |
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Local reactions, anticholinergic effects (eg, dry mouth, constipation, drowsiness, blurred vision), headache, GI upset, rash. |
| How Supplied |
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Patches—8, 24 |
| Additional Resources |
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• Related Prescribing Note |
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