Monograph Details
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Urogenital System
> Miscellaneous urogenital disorders
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UROCIT-K |
| Manufacturer |
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Mission Pharmacal Company |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Urinary alkalinizer. |
| Generic Name |
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Potassium citrate 5mEq (540mg); 10mEq (1080mg); tabs. |
| Indications |
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Renal tubular acidosis with calcium stones. Hypocitraturic calcium oxalate nephrolithiasis. Uric acid lithiasis. |
| Children |
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Not recommended. |
| Adults |
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Take within 30 minutes of meals or bedtime snack. Adjust based on urinary citrate levels and/or pH. Urinary citrate <150mg/day: 20mEq 3 times daily, or 15mEq 4 times daily. Urinary citrate >150mEq/day: 10mEq 3 times daily. Max 100mEq/day. |
| Contraindications |
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See literature. Hyperkalemia or predisposing conditions. GI narrowing or stricture, delayed gastric emptying or predisposing conditions. Peptic ulcer disease. UTI. Renal insufficiency (GFR <0.7mL/kg per minute). |
| Precautions |
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Restrict salt intake and encourage high fluid intake. Discontinue if severe vomiting, GI pain or bleeding occurs and follow-up. Monitor 24 hour urinary citrate, urinary pH, serum electrolytes, CBC, ECG, at least every 4 months; discontinue if hyperkalemia, significant rise in serum creatinine, or significant fall in hematocrit or hemoglobin occurs. Pregnancy (Cat.C). Nursing mothers. |
| Interactions |
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Contraindicated with potassium-sparing diuretics, anticholinergics, other drugs that slow GI motility. Monitor digoxin. May interfere with some urinary tract antibiotics. Caution with drugs that raise serum potassium. |
| Adverse Reactions |
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Hyperkalemia, GI upset, irritation, bleeding. |
| How Supplied |
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Tabs—100 |
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