Monograph Details
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Urogenital System
> Miscellaneous urogenital disorders
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RIMSO-50 |
| Manufacturer |
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Edwards Lifesciences Research Medical |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Antiinflammatory. |
| Generic Name |
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Dimethyl sulfoxide 50%; aqueous soln for intravesical administration. |
| Indications |
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Symptomatic relief of interstitial cystitis. |
| Children |
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Not recommended. |
| Adults |
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1 bottle (50mL) via catheter or aseptic syringe directly into the bladder for 15 minutes every 2 weeks until asymptomatic; then may increase dosing interval. To reduce bladder spasm: use a local anesthetic gel + an oral analgesics or belladona and opium suppositories before administration. |
| Precautions |
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Refer for full eye evaluation, including slit lamp, at baseline and periodically. Monitor CBC, liver and renal function every 6 months. Urinary tract malignancy. Pregnancy (Cat.C). Nursing mothers. |
| Interactions |
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May potentiate other concomitantly administered medications. |
| Adverse Reactions |
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Garlic-like taste or odor (may last for 72 hours), local discomfort, transient chemical cystitis. |
| How Supplied |
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Soln (50mL)—1 |
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