Monograph Details
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Respiratory Tract
> Cough and cold
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SEMPREX-D |
| Manufacturer |
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UCB Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Antihistamine + sympathomimetic. |
| Generic Name |
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Acrivastine 8mg, pseudoephedrine HCl 60mg; caps. |
| Indications |
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Seasonal allergic rhinitis symptoms. |
| Children |
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Not recommended. |
| Adults |
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1 cap every 4–6 hours, max 4/day. |
| Contraindications |
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Severe hypertension or coronary artery disease. During or within 14 days of MAOIs. |
| Precautions |
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Hypertension. Diabetes. Ischemic heart disease. Increased intraocular pressure. Hyperthyroidism. GI or GU obstruction. Elderly. Pregnancy (Cat.B). Renal impairment (CrCl <48mL/minute), nursing mothers: not recommended. |
| Interactions |
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Hypertensive crisis with MAOIs. β-blockers may increase the pressor effects of sympathomimetics. Alcohol, other CNS depressants potentiated. Antagonizes guanethidine, other antihypertensives. |
| Adverse Reactions |
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Somnolence, dry mouth, nervousness, insomnia, ephedrine-like reactions (tachycardia, palpitations, headache, dizziness, nausea). |
| How Supplied |
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Caps—100 |
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