Monograph Details
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Respiratory Tract
> Cough and cold
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EXTENDRYL SR |
| Manufacturer |
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Auriga Laboratories, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Antihistamine + sympathomimetic + anticholinergic. |
| Generic Name |
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Chlorpheniramine maleate 8 mg, phenylephrine HCl 20 mg, methscopolamine nitrate 2.5 mg; ext-rel caps. |
| Also |
• EXTENDRYL CHEWABLE TABLETS
• EXTENDRYL JR
• EXTENDRYL SYRUP
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| Indications |
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Rhinorrhea and congestion. |
| Children |
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<6 years: not recommended. ≥6 years: 1 Extendryl JR cap every 12 hours. |
| Adults |
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1 Extendryl SR cap every 12 hours. |
| Contraindications |
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During or within 14 days of MAOIs. Concomitant ergotamines: not recommended. Uncontrolled hypertension. Cardiac disease. Renal or hepatic dysfunction. Bronchospasm. Glaucoma. Diabetes. Pregnancy (Cat.C). Nursing mothers. |
| Precautions |
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Hypertension. Arrhythmias. GI or GU obstruction. Hyperthyroidism. History of bronchospasm. High environmental temperatures. Elderly. Labor & delivery. Young children. |
| Interactions |
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Hypertensive crisis with MAOIs. β-blockers may increase the pressor effects of sympathomimetics. Alcohol, other CNS depressants potentiated. Arrhythmias with digoxin. Guanethidine, other antihypertensives antagonized. Separate dosing of ketoconazole, antacids or adsorbent antidiarrheals by 2–3 hours. |
| Adverse Reactions |
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Drowsiness, anticholinergic effects, GI upset, dizziness, anxiety, weakness, insomnia, thickening of bronchial secretions, hypertension, hypotension, excitability in children, respiratory depression or difficulty, palpitations. |
| How Supplied |
Tabs, SR, JR—100
Syrup—pt |
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