Monograph Details
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Respiratory Tract
> Cough and cold
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EXTENDRYL CHEWABLE TABLETS |
| Manufacturer |
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Auriga Laboratories, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Antihistamine + sympathomimetic + anticholinergic. |
| Generic Name |
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Chlorpheniramine maleate 2mg, phenylephrine HCl 10 mg, methscopolamine nitrate 1.25mg; chew tabs (scored). |
| Also |
• EXTENDRYL JR
• EXTENDRYL SR
• EXTENDRYL SYRUP
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| Indications |
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Rhinorrhea and congestion. |
| Children |
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<6 years: not recommended. ≥6 years: 1 tab every 4 hours; max 4 doses/day. |
| Adults |
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1–2 tabs every 4 hours; max 4 doses/day. |
| Contraindications |
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During or within 14 days of MAOIs. Concomitant ergotamines: not recommended. Uncontrolled hypertension. Cardiac disease. Renal or hepatic dysfunction. Bronchospasm. Glaucoma. Diabetes. Pregnancy (Cat.C). Nursing mothers. |
| Precautions |
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Hypertension. Arrhythmias. GI or GU obstruction. Hyperthyroidism. History of bronchospasm. High environmental temperatures. Elderly. Labor & delivery. Young children. |
| Interactions |
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Hypertensive crisis with MAOIs. β-blockers may increase the pressor effects of sympathomimetics. Alcohol, other CNS depressants potentiated. Arrhythmias with digoxin. Guanethidine, other antihypertensives antagonized. Separate dosing of ketoconazole, antacids or adsorbent antidiarrheals by 2–3 hours. |
| Adverse Reactions |
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Drowsiness, anticholinergic effects, GI upset, dizziness, anxiety, weakness, insomnia, thickening of bronchial secretions, hypertension, hypotension, excitability in children, respiratory depression or difficulty, palpitations. |
| How Supplied |
Tabs, SR, JR—100
Syrup—pt |
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