Monograph Details
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Respiratory Tract
> Cough and cold
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ALLERX PE |
| Manufacturer |
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Cornerstone BioPharma, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Sympathomimetic + antihistamine (PM tab only) + anticholinergic. |
| Generic Name |
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Phenylephrine HCl 40mg + methscopolamine nitrate 2.5mg; per AM tab; phenylephrine HCl 10mg, chlorpheniramine maleate 8mg + methscopolamine nitrate 2.5mg; per PM tab; scored. |
| Indications |
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Rhinorrhea and congestion. |
| Children |
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Not recommended. |
| Adults |
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1 AM tab in the morning and 1 PM tab in the evening. |
| Contraindications |
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Severe hypertension or coronary artery disease. During or within 14 days of MAOIs. Narrow-angle glaucoma. Urinary retention. Peptic ulcer. Acute asthma. Nursing mothers. |
| Precautions |
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Hypertension. Diabetes. Ischemic heart or cardiovascular disease. Hyperthyroidism. Increased intraocular pressure. GU or GI obstruction. Hepatic or renal impairment. Autonomic neuropathy. Ulcerative colitis. Young children. Elderly. Pregnancy (Cat.C). |
| Interactions |
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MAOIs and β-blockers increase the effects of sympathomimetics. Guanethidine, other antihypertensives antagonized. Increased anticholinergic effects with antipsychotics and tricyclic antidepressants. Antacids may interfere with methscopolamine absorption. |
| Adverse Reactions |
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Drowsiness, anticholinergic effects, GI upset, dizziness, headache, nervousness, insomnia, flushing, irritability, hypotension, respiratory difficulty, palpitations. |
| How Supplied |
Dose pack (20 tabs)—1 (10 AM tabs + 10 PM tabs)
Dose pack (60 tabs)—1 (30 AM tabs + 30 PM tabs) |
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