Monograph Details
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Respiratory Tract
> Asthma/COPD
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PULMICORT RESPULES |
| Manufacturer |
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AstraZeneca Pharmaceuticals |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Steroid. |
| Generic Name |
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Budesonide (micronized) 0.25mg/2mL, 0.5mg/2mL, 1mg/2mL; susp for inhalation. |
| Also |
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• PULMICORT FLEXHALER
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| Indications |
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Maintenance treatment of asthma and as prophylactic therapy. |
| Children |
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Use jet nebulizer; do not mix with other drugs. <6months: not recommended. 6–12months: see literature. 12months–8yrs: Previously on bronchodilators alone: 0.5mg/day once daily or in 2 divided doses (if symptomatic and unresponsive to nonsteroidal therapy, may start at 0.25mg once daily). Previously on inhaled corticosteroids: 0.5mg/day once daily or in 2 divided doses; max 1mg/day. Previously on oral corticosteroids: 1mg/day once daily or in 2 divided doses. Rinse mouth and face (if face mask used) after use. |
| Adults |
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Use Flexhaler. |
| Contraindications |
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Not for primary treatment of acute attack. |
| Precautions |
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Maintain regular regimen. Infections. If exposed to chickenpox or measles, consider antiinfective prophylactic therapy. Adrenal insufficiency may occur when transferring patients from systemic corticosteroids to inhaled corticosteroids: see literature. Monitor for growth suppression in children. Post-op or during stress: monitor adrenal response. Monitor for hypercorticism and HPA axis suppression (if occur discontinue gradually). Transferring from oral corticosteroids: see literature. Pregnancy (Cat.B). Nursing mothers: not recommended. |
| Interactions |
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Caution with CYP3A4 inhibitors (eg, ketoconazole). |
| Adverse Reactions |
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Pulmicort Flexhaler: nasal congestion, allergic rhinitis, viral upper respiratory tract infection, oral candidiasis, viral gastroenteritis, nausea, bronchospasm (rare). Pulmicort Respules: Respiratory or other infection, GI upset, moniliasis, fatigue, cough, dysphonia, rash, epistaxis, bronchospasm (rare). |
| How Supplied |
Flexhaler (90mcg/dose)—1 (60 inh)
Flexhaler (180mcg/dose)—1 (120 inh)
Respules—30 |
| Additional Resources |
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• Related Prescribing Note |
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