Monograph Details
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Pain & Pyrexia
> Nonnarcotic analgesics
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NEURONTIN CAPSULES |
| Manufacturer |
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Pfizer Labs |
| Legal Classification |
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Rx
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| Generic Name |
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Gabapentin 100mg, 300mg, 400mg. |
| Also |
• NEURONTIN ORAL SOLN
• NEURONTIN TABLETS
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| Indications |
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Postherpetic neuralgia. |
| Children |
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Not recommended. |
| Adults |
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300mg once on day 1, twice daily on day 2, and 3 times daily on day 3; may titrate up to usual max 1.8g/day in 3 divided doses (doses up to 3.6g/day have been used without added benefit). Renal dysfunction: CrCl 30–59mL/min: 400–1400mg/day twice daily; CrCl 15–29mL/min: 200–700mg once daily; CrCl ≤15mL/min: 100–300mg once daily (see literature); hemodialysis: 125–350mg after session. |
| Precautions |
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Renal dysfunction. Suicidal tendencies (monitor). Avoid abrupt cessation. Elderly. Pregnancy (Cat.C). Nursing mothers. |
| Interactions |
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Potentiates CNS depression with alcohol, morphine, other CNS depressants. Give 2 hrs after antacids. May antagonize hydrocodone. May interfere with some urine protein tests (eg, Multistix-SG). |
| Adverse Reactions |
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Dizziness, somnolence, peripheral edema, GI upset, ataxia, visual disturbances, thought disorder, abnormal gait, incoordination. |
| How Supplied |
Caps, tabs—100
Soln—470mL |
| Additional Resources |
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• Related Prescribing Note |
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