Monograph Details
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Pain & Pyrexia
> Nonnarcotic analgesics
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NALFON |
| Manufacturer |
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Pedinol Pharmacal, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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NSAID (arylacetic acid deriv.). |
| Generic Name |
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Fenoprofen calcium 200mg; caps. |
| Indications |
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Mild to moderate pain. |
| Children |
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<18yrs: not recommended. |
| Adults |
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200mg every 4–6hrs as needed. |
| Contraindications |
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Aspirin allergy. CABG surgery. Significant renal impairment. 3rd trimester pregnancy. |
| Precautions |
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Hypertension. CHF. Edema. History of ulcer disease or GI bleeding. Hearing impaired. Asthma. Monitor blood, hepatic, renal, and ocular function in chronic use. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers: not recommended. |
| Interactions |
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Avoid aspirin. May potentiate protein-bound drugs (eg, hydantoins, sulfonamides, sulfonylureas). May antagonize ACE-inhibitors, diuretics. May be antagonized by phenobarbital. Increased risk of GI bleed with oral corticosteroids, anticoagulants (monitor), alcohol, smoking. Methotrexate excretion reduced. Increases lithium levels. |
| Adverse Reactions |
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GI upset, dyspepsia, constipation, tremor, confusion, increased sweating, pruritus, rash (discontinue if occurs), tinnitus, blurred vision, decreased hearing, palpitations, nervousness, asthenia, peripheral edema, dyspnea; GI ulcer/bleed, elevated liver enzymes (discontinue if hepatotoxicity develops), blood dyscrasias, renal papillary necrosis. See literature re: risk of cardiovascular events. |
| How Supplied |
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Caps—100 |
| Additional Resources |
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• Related Prescribing Note |
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