Monograph Details
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Pain & Pyrexia
> Nonnarcotic analgesics
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MOTRIN TABLETS |
| Manufacturer |
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Pfizer Labs |
| Legal Classification |
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Rx
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| Pharmacological Class |
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NSAID (propionic acid deriv.). |
| Generic Name |
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Ibuprofen 400mg, 600mg, 800mg. |
| Also |
• MOTRIN CAPLETS
• MOTRIN ORAL DROPS
• MOTRIN SUSPENSION
• MOTRIN CHEWABLE
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| Indications |
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Mild to moderate pain. Fever. |
| Children |
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Use caplets, chewables, suspension, or drops. <6 months: not recommended. ≥6 months: Fever <102.5°F: 5mg/kg every 6–8 hours. Fever >102.5°F or pain: 10mg/kg every 6–8 hours; max 40mg/kg/day. |
| Adults |
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Pain: 400mg every 4–6 hrs as needed. |
| Contraindications |
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Aspirin allergy. 3rd trimester pregnancy. Coronary artery bypass graft surgery. |
| Precautions |
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Advanced renal disease: not recommended. History of upper GI disease. Active peptic ulcer. Impaired renal or hepatic function. Edema. Hypertension. Cardiac failure. Bleeding disorders. Diabetes. Monitor blood, hepatic, renal, and ocular function in chronic use. Discontinue if visual or liver dysfunction occurs. Dehydration. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers: not recommended. |
| Interactions |
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Avoid aspirin. May increase bleeding with anticoagulants, toxicity of methotrexate. Increases serum lithium levels. May decrease effect of furosemide, thiazide diuretics. |
| Adverse Reactions |
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Peptic ulcer or perforation, GI bleeding, vision disorders, nausea, epigastric pain, heartburn, dizziness, rash (discontinue if occurs), edema, renal papillary necrosis, jaundice, hepatitis. See literature re: risk of cardiovascular events. |
| How Supplied |
Tablets—100, 500
Caplets, chew tabs—100
Susp—4oz, 16oz
Drops—15mL |
| Additional Resources |
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• Related Prescribing Note |
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