Monograph Details
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Pain & Pyrexia
> Nonnarcotic analgesics
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BAYER |
| Manufacturer |
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Bayer Corp, Consumer Care Div. |
| Legal Classification |
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OTC |
| Pharmacological Class |
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Salicylate. |
| Generic Name |
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Aspirin 325mg; tabs; caplets; gelcaps. |
| Indications |
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Pain. Fever. |
| Children |
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Use chewable tabs. |
| Adults |
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325–650mg every 4 hours. |
| Contraindications |
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NSAID allergy. Viral infection in children and teenagers. 3rd trimester pregnancy. |
| Precautions |
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History of asthma or peptic ulcer. Severe hepatic or renal dysfunction. Bleeding disorders. Diabetes. Gout. Pregnancy, nursing mothers: not recommended. |
| Interactions |
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Potentiates anticoagulants, hypoglycemics, methotrexate, acetazolamide, valproic acid, highly protein-bound drugs. Urinary alkalinizers, antacids, corticosteroids may increase excretion. May antagonize ACE inhibitors, β-blockers, diuretics, uricosurics. Increased bleeding risk with NSAIDs or chronic, heavy alcohol use. NSAIDs increase risk of renal dysfunction. |
| Adverse Reactions |
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GI upset/bleed, prolonged bleeding time, anaphylaxis, salicylism. |
| How Supplied |
Tabs—12, 24, 50, 100, 200, 300, 365
Caplets—50, 100, 200
Gelcaps—40, 80
Ext Str tabs, caplets, Plus—50
Ext Str Gelcaps—40, 80
Children's—36 |
| Additional Resources |
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• Related Prescribing Note |
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