Monograph Details
|
|
Pain & Pyrexia
> Narcotic analgesics
|
|
PERCODAN |
| Manufacturer |
|
Endo Pharmaceuticals |
| Legal Classification |
|
CII |
| Pharmacological Class |
|
Opioid + salicylate. |
| Generic Name |
|
Oxycodone HCl 4.8355mg, aspirin 325mg; scored tabs. |
| Indications |
|
Moderate to moderately severe pain. |
| Children |
|
Not recommended. |
| Adults |
|
1 tab every 6 hrs as needed. |
| Contraindications |
|
NSAID allergy. Varicella or influenza in children and teenagers. Severe bleeding or coagulation disorders. Peptic ulcer. 3rd trimester pregnancy. |
| Precautions |
|
Asthma. Head injury. Increased intracranial pressure. Acute abdomen. Impaired renal, hepatic, thyroid, or adrenocortical function. GI or GU obstruction. Gastritis. Monitor blood pressure, BUN, uric acid levels. Drug abusers. Elderly. Debilitated. Pregnancy. Nursing mothers. |
| Interactions |
|
Potentiated by alcohol, CNS depressants, anticoagulants, hypoglycemics, protein-bound drugs, MAOIs, tricyclic antidepressants, anticholinergics. Alcohol, NSAIDs, corticosteroids increase risk of GI bleed. May antagonize uricosurics, antihypertensives. May potentiate acetazolamide. |
| Adverse Reactions |
|
Dizziness, sedation, GI upset, constipation, urinary retention, allergic reactions, respiratory depression; overdosage: hepatotoxicity, salicylism. |
| How Supplied |
|
Tabs—100 |
|
|
|
|
