Monograph Details
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Pain & Pyrexia
> Narcotic analgesics
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NUBAIN |
| Manufacturer |
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Endo Pharmaceuticals |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Opioid (agonist-antagonist). |
| Generic Name |
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Nalbuphine HCl 10mg/mL, 20mg/mL; SC, IM or IV inj; vials (sulfite-free, contains parabens); amps (sulfite- and paraben-free). |
| Indications |
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Moderate to severe pain. Pre-op and post-op pain. Supplement to anesthesia. Prepartum pain. |
| Children |
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<18yrs: not recommended. |
| Adults |
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10mg/70kg IM, SC or IV every 3–6 hours as needed. |
| Precautions |
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Head injury. Increased intracranial pressure. Biliary tract surgery. Impaired respiratory, cardiac, renal, or hepatic function. MI. Hypertension. Drug abusers. Asthma (sulfites). Labor and delivery (esp. premature). Pregnancy. |
| Interactions |
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Potentiation with alcohol, CNS depressants. May precipitate withdrawal in narcotic addicts. |
| Adverse Reactions |
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Sedation, diaphoresis, nausea, dizziness, dry mouth, headache, depression, dependence, possible withdrawal after prolonged use. |
| How Supplied |
Inj multidose vials (10mL)—1
Inj amps (1mL)—10 |
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