Monograph Details
|
|
Pain & Pyrexia
> Narcotic analgesics
|
|
MAGNACET 2.5mg/400mg |
| Manufacturer |
|
Mallinckrodt, Inc. |
| Legal Classification |
|
CII |
| Pharmacological Class |
|
Opioid + analgesic. |
| Generic Name |
|
Oxycodone HCl 2.5mg, acetaminophen 400mg; tabs. |
| Also |
• MAGNACET 10mg/400mg
• MAGNACET 5mg/400mg
• MAGNACET 7.5mg/400mg
|
| Indications |
|
Moderate to moderately severe pain. |
| Children |
|
Not recommended. |
| Adults |
|
1–2 tabs every 6 hrs; max 10 tabs/day. Max 4g of acetaminophen per day. |
| Precautions |
|
Head injury. Increased intracranial pressure. Acute abdominal conditions. Severe pulmonary, renal, hepatic, thyroid, or adrenocortical dysfunction. Asthma. GI or GU obstruction. Drug abusers. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat.C). Nursing mothers. |
| Interactions |
|
Potentiation with alcohol, other CNS depressants, MAOIs, tricyclics, phenothiazines. Anticholinergics may cause paralytic ileus. |
| Adverse Reactions |
|
Lightheadedness, dizziness, sedation, nausea, vomiting, euphoria, dysphoria, constipation, rash, pruritus; overdosage: respiratory depression, hepatotoxicity. |
| How Supplied |
|
Tabs—100 |
|
|
|
|
