Monograph Details
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Pain & Pyrexia
> Narcotic analgesics
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HYCET |
| Manufacturer |
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Xanodyne Pharmacal, Inc. |
| Legal Classification |
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CIII |
| Pharmacological Class |
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Opioid + analgesic. |
| Generic Name |
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Hydrocodone bitartrate 7.5mg, acetaminophen 325mg; per 15mL soln; contains alcohol (7%); tropical fruit punch flavor. |
| Indications |
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Moderate to moderately severe pain. |
| Children |
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<2yrs: not recommended. 2–3yrs (27–34 lbs): 3.75mL. 4–6yrs (35–50 lbs): 5mL. 7–9yrs (51–69 lbs): 7.5mL. 10–13yrs (70–100 lbs): 10mL. All: give every 4–6 hours as needed. |
| Adults |
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≥14yrs (≥101 lbs): 15mL every 4–6 hours as needed; max 120mL/day. |
| Precautions |
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Head injury. Increased intracranial pressure. Acute abdomen. Impaired renal, hepatic, thyroid, pulmonary, or adrenocortical function. GI or GU obstruction. Post-op use. Drug abusers. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat.C) (neonatal withdrawal syndrome). Nursing mothers: not recommended. |
| Interactions |
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Potentiation with alcohol, other CNS depressants (eg, antihistamines, antipsychotics, antianxiety drugs). May potentiate or be potentiated by MAOIs, tricyclic antidepressants. |
| Adverse Reactions |
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CNS/respiratory/circulatory depression, hypotension, dizziness, GI upset, constipation, urinary retention, rash; hepatotoxicity (overdosage). |
| How Supplied |
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Soln—473mL (1 pint) |
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