Monograph Details
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Pain & Pyrexia
> Narcotic analgesics
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DARVON COMPOUND 32 |
| Manufacturer |
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Xanodyne Pharmacal, Inc. |
| Legal Classification |
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CIV |
| Pharmacological Class |
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Opioid + salicylate. |
| Generic Name |
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Propoxyphene HCl 32mg, aspirin 389mg, caffeine 32.4mg; caps. |
| Also |
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• DARVON COMPOUND 65
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| Indications |
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Mild to moderate pain. |
| Children |
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Not recommended. |
| Adults |
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1 cap every 4 hrs as needed; max 390mg propoxyphene/day. |
| Contraindications |
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NSAID allergy. Varicella or influenza in teenagers. Suicidal or addiction-prone patients. Severe bleeding or coagulation disorders. Peptic ulcer. 3rd trimester pregnancy. |
| Precautions |
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Asthma. Renal or hepatic impairment. GI bleeding. Monitor blood pressure, BUN, uric acid levels. Depression. Suicidal ideation. Elderly. Debilitated. Pregnancy. Nursing mothers. |
| Interactions |
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CNS depression potentiated by alcohol, other CNS depressants. May potentiate anticoagulants, hypoglycemics, antidepressants, anticonvulsants, protein bound drugs. Alcohol, NSAIDs, corticosteroids increase risk of GI bleeding. May antagonize uricosurics. Severe neurological effects (eg, coma) possible with carbamazepine. |
| Adverse Reactions |
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Dizziness, sedation, GI upset, constipation, allergic reactions, rash, prolonged bleeding time; overdosage: respiratory depression, salicylism. |
| How Supplied |
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Caps—100 |
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