Monograph Details
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Pain & Pyrexia
> Migraine and headache
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MIDRIN |
| Manufacturer |
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Women First HealthCare |
| Legal Classification |
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CIV |
| Pharmacological Class |
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Sympathomimetic + sedative + analgesic. |
| Generic Name |
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Isometheptene mucate 65mg, dichloralphenazone 100mg, acetaminophen 325mg; caps. |
| Indications |
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Tension and vascular headache. Migraine. |
| Children |
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Not recommended. |
| Adults |
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Tension: 1–2 caps every 4 hours; max 8 caps/day. Migraine: 2 caps once then 1 cap every 1 hour; max 5 caps/12 hours. |
| Contraindications |
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Glaucoma. Severe renal, cardiac, hypertensive, or hepatic disease. Acute intermittent porphyria. Concurrent MAOIs. |
| Precautions |
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Peripheral vascular disease. Recent MI. Gastritis. Hypertension. Nursing mothers. |
| Interactions |
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Hypertensive crisis with MAOIs. May potentiate oral anticoagulants. |
| Adverse Reactions |
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Dizziness, drowsiness, sympathomimetic effects, rash. |
| How Supplied |
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Caps—50, 100, 250 |
| Additional Resources |
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• Related Prescribing Note |
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