Monograph Details
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Pain & Pyrexia
> Migraine and headache
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EXCEDRIN MIGRAINE |
| Manufacturer |
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Novartis Consumer Health |
| Legal Classification |
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OTC |
| Pharmacological Class |
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Analgesic + salicylate. |
| Generic Name |
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Acetaminophen 250mg, aspirin 250mg, caffeine 65mg; tabs. |
| Indications |
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Migraine. |
| Children |
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Not recommended. |
| Adults |
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Take with full glass of water. ≥18yrs: 2 tabs every 6 hours as needed; max 8 tabs/day for 2 days. |
| Contraindications |
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NSAID allergy. Varicella, vaccinia in children and teenagers. 3rd trimester of pregnancy. |
| Precautions |
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Persistent or unresponsive headache. History of asthma or peptic ulcer. Impaired hepatic or renal function. Bleeding disorders. Erosive gastritis. Diabetes. Gout. Pregnancy. Nursing mothers: not recommended. |
| Interactions |
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PABA may increase serum aspirin levels. May potentiate anticoagulants, hypoglycemics, methotrexate. Urinary alkalinizers, antacids, corticosteroids may increase aspirin excretion. May antagonize uricosurics, spironolactone. Increased risk of liver toxicity and/or GI bleed with alcohol. |
| Adverse Reactions |
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Gastric upset, prolonged bleeding time, urticaria, anaphylaxis; overdosage: salicylism, hepatoxicity. |
| How Supplied |
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Tabs—24, 50, 100 |
| Additional Resources |
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• Related Prescribing Note |
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