Monograph Details
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Ob/Gyn
> Vaginal infections
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VANDAZOLE |
| Manufacturer |
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Upsher-Smith Laboratories, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Antibacterial (imidazole). |
| Generic Name |
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Metronidazole 0.75%; vaginal gel; contains parabens. |
| Indications |
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Bacterial vaginosis. |
| Children |
Pre-menarchal: not recommended.
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| Adults |
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One applicatorful once daily at bedtime, or twice daily, for 5 days. |
| Precautions |
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Discontinue if abnormal neurological signs develop. CNS or hepatic disease. Do not have vaginal intercourse or use tampons or douches during therapy. Pregnancy (Cat.B). Nursing mothers: not recommended. |
| Interactions |
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Avoid concomitant alcohol. Do not give within 2 weeks of disulfiram (possible psychotic reactions). May potentiate oral anticoagulants, lithium. May be potentiated by cimetidine. May interfere with serum chemistry tests. |
| Adverse Reactions |
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Fungal infection, headache, pruritus, abdominal pain, GI upset, dysmenorrhea, pharyngitis. |
| How Supplied |
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Gel—70g (w. applicators) |
| Additional Resources |
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• Related Prescribing Note |
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