Monograph Details
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Ob/Gyn
> Miscellaneous Ob/Gyn conditions
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DEPO-SUBQ PROVERA |
| Manufacturer |
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Pfizer Labs |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Progestin. |
| Generic Name |
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Medroxyprogesterone acetate 104mg/0.65mL; SC inj; contains parabens. |
| Indications |
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Pain due to endometriosis. |
| Children |
Not applicable.
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| Adults |
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Inject 104mg SC every 3 months. Give 1st dose within 5 days of onset of normal menses. Do not use for >2 years unless other methods are inadequate. |
| Contraindications |
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Undiagnosed vaginal bleeding. Breast carcinoma. Cerebrovascular disease. Hepatic dysfunction. Pregnancy (Cat.X). |
| Precautions |
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May be used as contraceptive; other hormonal contraceptives: not recommended. Conditions aggravated by fluid retention (eg, migraine). Depression. Pretreatment exam should include Pap smear. Risk of osteoporosis (eg, metabolic bone disease, anorexia, family history). Discontinue if jaundice, visual disturbances, migraine or thrombotic disorders occur. Nursing mothers. |
| Interactions |
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May be antagonized by aminoglutethimide. May reduce bone mass with anticonvulsants, corticosteroids; avoid alcohol, tobacco. |
| Adverse Reactions |
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Irregular bleeding, edema, weight or cervical changes, decreased bone mineral density, cholestatic jaundice, depression, breast tenderness, acne, hirsutism, inj site reactions. |
| How Supplied |
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Prefilled syringe—1 (w. needle) |
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