Monograph Details
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Ob/Gyn
> Infertility
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SEROPHENE |
| Manufacturer |
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EMD Serono, Inc. |
| Legal Classification |
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Rx
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| Generic Name |
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Clomiphene citrate 50mg; scored tabs. |
| Indications |
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Induction of ovulation. |
| Children |
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Not applicable. |
| Adults |
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50mg daily for 5 days beginning on the 5th day of menstrual cycle; max 3 courses. If ovulation does not occur after 1st course, increase dose to 100mg daily for 2nd course; max 100mg/day for 5 days. See literature. |
| Contraindications |
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Primary ovarian failure. Ovarian cysts. Uterine leiomyomas. Abnormal uterine bleeding. Thrombophlebitis. Liver disease. Depression. Uncontrolled thyroid or adrenal dysfunction. Intracranial lesions. Pregnancy (Cat.X). |
| Precautions |
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Perform initial complete pelvic and endocrinologic exam. Discontinue if visual disorders occur. Nursing mothers. |
| Adverse Reactions |
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Ovarian enlargement, hot flashes, abdominal discomfort, abnormal uterine bleeding, mastodynia, visual disturbances, multiple births. |
| How Supplied |
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Tabs—10, 30 |
| Additional Resources |
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• Related Prescribing Note |
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