Monograph Details
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Ob/Gyn
> Contraception
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LOESTRIN 24 Fe |
| Manufacturer |
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Warner Chilcott Laboratories |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Progestin + estrogen. |
| Generic Name |
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Norethindrone acetate 1mg, ethinyl estradiol 20micrograms (24 tabs); inert+ (4 tabs). +contains ferrous fumarate 75mg. |
| Also |
• LOESTRIN 21 1/20
• LOESTRIN 21 1.5/30
• LOESTRIN Fe 1/20
• LOESTRIN Fe 1.5/30
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| Indications |
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Oral contraception. |
| Children |
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Not applicable. |
| Adults |
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28-day products: 1 tab daily for 28 days; repeat. 21-day products: 1 tab daily for 21 days, then 7 tablet-free days; repeat. |
| Contraindications |
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Thrombophlebitis or thromboembolic disorders. Cerebral vascular or coronary artery disease. Breast or other estrogen-dependent neoplasms. Undiagnosed abnormal genital bleeding. Cholestatic jaundice of pregnancy or jaundice with prior OC use. Hepatic adenoma or carcinoma. Pregnancy (Cat.X). |
| Precautions |
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Smokers over 35 years of age: not recommended. Uncontrolled hypertension. Hypertriglyceridemia. Discontinue if jaundice, visual disturbances, migraine or other severe headaches occur. Do regular complete physical exams. May need barrier contraception with Sunday starts or postpartum use (see literature). Nursing mothers: not recommended. |
| Interactions |
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Antagonized by hepatic enzyme inducing drugs (eg, rifampin, griseofulvin, St. John's wort), possibly others. May affect measurement of sex hormone-binding globulin levels. |
| Adverse Reactions |
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Hypertension, nausea, vomiting, breakthrough bleeding, amenorrhea, transient delay of ovulation after discontinuation, edema, chloasma, mastodynia, headache, intolerance to contact lenses. Increased risk of gallbladder disease, thromboembolic disorders. |
| How Supplied |
Packs (24 Fe, 21-1/20, 21-1.5/30)—5
Packs (Fe 1/20, Fe 1.5/30)—5, 30 |
| Additional Resources |
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• Related Prescribing Note |
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