Monograph Details
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Ob/Gyn
> Contraception
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IMPLANON |
| Manufacturer |
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Schering Corporation |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Progestin. |
| Generic Name |
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Etonogestrel 68mg; implantable rod; latex-free. |
| Indications |
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Subdermal contraception. |
| Children |
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Premenarchal: not applicable. |
| Adults |
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Insert 1 implant subdermally in the inner side of upper (non-dominant) arm. Remove no later than 3 years after insertion. |
| Contraindications |
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Breast carcinoma. Undiagnosed abnormal genital bleeding. Active liver disease. Liver tumors. Pregnancy. Thromboembolic disease. |
| Precautions |
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Overweight women (may be less effective). Do complete physical exam before insertion and at least annually. Exclude pregnancy (see literature for switching from other contraceptive methods); use back-up contraception if appropriate. See literature for insertion and removal technique; perform only if properly qualified. Remove implant if jaundice or thrombotic event occurs, or if a pregnancy is maintained; consider removing implant in prolonged immobilization. Hypertension. Renal disease. Depression. Monitor diabetes, hyperlipidemias. Nursing mothers: may use after 4th postpartum week. |
| Interactions |
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Chronic antiepileptic or other potent hepatic enzyme-inducing drugs (eg, barbiturates, phenytoin, carbamazepine, rifampin, felbamate, modafinil): not recommended. May be antagonized by other hepatic enzyme inducers (eg, St. John's wort, protease inhibitors); use non-hormonal contraception. Levels increased by ketoconazole, itraconazole, other hepatic enzyme inhibitors. May affect measurement of sex hormone-binding globulin, thyroxine. |
| Adverse Reactions |
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Headache, vaginitis, weight increase, acne, mastodynia, menstrual irregularities (eg, amenorrhea, changes in bleeding patterns), abdominal pain (exclude ectopic pregnancy), leukorrhea, dizziness, back pain, emotional lability, nausea, depression, insertion site pain; thrombotic events, others (see literature). |
| Extra Text |
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Note: Provide adequate counseling. Obtain signed written consent (see literature). |
| How Supplied |
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Rod implant (w. insertion device)—1 |
| Additional Resources |
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• Related Prescribing Note |
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