Monograph Details
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Nutrition
> Obesity
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Diethylpropion |
| Manufacturer |
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Various generic manufacturers |
| Legal Classification |
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CIV |
| Pharmacological Class |
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Sympathomimetic. |
| Generic Name |
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Diethylpropion HCl 25mg; tabs. |
| Also |
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• Diethylpropion sustained-release tabs
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| Indications |
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Short-term adjunct in management of exogenous obesity. |
| Children |
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Not recommended. |
| Adults |
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25mg 3 times daily 1 hr before meals and in midevening for night hunger or one 75mg sustained-release tab daily in midmorning. |
| Contraindications |
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Arteriosclerosis. Hypertension. Hyperthyroidism. Glaucoma. Agitation. Drug or alcohol abuse. During or within 14 days of MAOIs. |
| Precautions |
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Discontinue after a few weeks as tolerance to anorectic effect occurs. Epilepsy. Cardiovascular disease. Arrhythmias. Diabetes. Prescribe limited supply to prevent overdose. Pregnancy (Cat.B). Nursing mothers. |
| Interactions |
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Hypertensive crisis with MAOIs. Blocks guanethidine. Adverse reaction with alcohol. Arrhythmias may occur with general anesthetics. Antagonized by phenothiazines. |
| Adverse Reactions |
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Abuse potential, impairment in hazardous activities, arrhythmias, hypertension, CNS overstimulation, psychosis, dry mouth, GI disturbances, urticaria, impotence, seizures, blood dyscrasias, dyspnea, hair loss, dysuria. |
| How Supplied |
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Contact supplier. |
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