Monograph Details
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Nutrition
> Obesity
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ALLI |
| Manufacturer |
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GlaxoSmithKline Pharmaceuticals |
| Legal Classification |
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OTC |
| Pharmacological Class |
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Lipase inhibitor. |
| Generic Name |
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Orlistat 60mg; caps. |
| Indications |
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Adjunct to reduced-calorie, low-fat diet for weight loss in overweight adults. |
| Children |
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<18yrs: not recommended. |
| Adults |
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≥18yrs: 1 cap with each fat-containing meal. Max: 180mg/day. Also, take a multivitamin once daily at bedtime. |
| Contraindications |
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Organ transplant. Chronic malabsorption syndrome. Cholestasis. |
| Precautions |
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Gallbladder disorder. Pancreatitis. Kidney stones. Pregnancy, nursing mothers: not recommended. |
| Interactions |
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Concomitant cyclosporine: not recommended. May decrease absorption of fat-soluble vitamins; supplement diet with a multivitamin (separate dosing by at least 2 hours). Monitor warfarin, antidiabetics, thyroid drugs; may need to adjust dose. |
| Adverse Reactions |
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GI effects (oily spotting, flatus with discharge, fecal urgency, fatty/oily stools, oily evacuation, increased defecation, fecal incontinence). |
| How Supplied |
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Caps—60, 90, 120 |
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