Monograph Details
|
|
Nutrition
> Formulas/metabolic disorders
|
|
CARNITOR INJECTION |
| Manufacturer |
|
Sigma-Tau Pharmaceuticals, Inc. |
| Legal Classification |
|
Rx
|
| Generic Name |
|
Levocarnitine 200mg/mL; soln for IV bolus inj or infusion; preservative-free. |
| Also |
• CARNITOR
• CARNITOR ORAL SOLUTION
• CARNITOR SF
|
| Indications |
|
Secondary carnitine deficiency. Carnitine deficiency in end stage renal disease (ESRD) patients undergoing dialysis. |
| Adults and Children |
|
Secondary carnitine deficiency: 50mg/kg IV as slow (2–3 minutes) bolus inj or by infusion; usual max 300mg/kg. May give loading dose in severe metabolic crisis: see literature. ESRD: initially 10–20mg/kg dry body weight as slow (2–3 minutes) IV bolus inj into venous return line after each dialysis session; adjust dose based on trough levocarnitine levels. |
| Precautions |
|
Obtain baseline carnitine level; monitor blood chemistry, carnitine levels, vital signs, clinical condition. Seizure disorders. Renal insufficiency (oral forms). Pregnancy (Cat.B). Nursing mothers: not recommended. |
| Adverse Reactions |
|
GI upset/pain, body odor, seizures; inj: hypercalcemia, local reactions. |
| How Supplied |
Tabs—90
Oral soln—4oz
Inj amps or vials (single-dose 5mL)—5 |
| Additional Resources |
|
• Related Prescribing Note |
|
|
|
|
