Monograph Details

Nutrition > Anorexia/cachexia
MEGACE ES
Manufacturer
Par Pharmaceutical, Inc.
Legal Classification
Rx
Pharmacological Class
Progestin.
Generic Name
Megestrol acetate 625mg/5mL (125mg/mL); oral susp; lemon-lime flavor.
Indications
Anorexia, cachexia, or unexplained significant weight loss in patients diagnosed with AIDS.
Children
Not recommended.
Adults
625mg/5mL per day.
Contraindications
Nursing mothers.
Precautions
Do not substitute with other megestrol suspensions (not interchangeable). History of thromboembolic disease. Diabetes. Pregnancy (Cat.X): not recommended.
Interactions
May increase insulin requirements. Decreases indinavir levels.
Adverse Reactions
GI upset, impotence, flatulence, rash, hypertension, fever, decreased libido, breakthrough bleeding, hyperglycemia, insomnia.
How Supplied
Concentrated susp (625mg/5mL)—5oz