Monograph Details
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Neoplasms
> Hormones and antagonists
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TRELSTAR DEPOT |
| Manufacturer |
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Watson Pharmaceuticals, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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GnRH analogue. |
| Generic Name |
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Triptorelin pamoate 3.75mg; pwd for IM inj after reconstitution. |
| Also |
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• TRELSTAR LA
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| Indications |
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Palliative treatment of advanced prostate cancer. |
| Children |
Not applicable.
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| Adults |
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3.75mg IM once per month. |
| Contraindications |
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Pregnancy (Cat.X). Nursing mothers. |
| Precautions |
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Discontinue if hypersensitivity occurs. Initial transient increase in serum testosterone may result in worsening of symptoms. Spinal cord compression. Renal impairment. Metastatic vertebral lesions. Upper or lower urinary tract obstruction. |
| Interactions |
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Avoid hyperprolactinemic drugs. |
| Adverse Reactions |
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Inj site reactions, hot flushes, bone pain, fatigue, hypertension, headache, dizziness, GI upset, leg edema, insomnia, impotence, emotional lability, anemia, pruritus, urinary retention, UTI. |
| How Supplied |
Single-dose vial—1
Clip 'n' Ject delivery system—1 (single-dose vial + prefilled syringe) |
| Additional Resources |
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• Related Prescribing Note |
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