Monograph Details
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Neoplasms
> Hormones and antagonists
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ELIGARD 45mg 6-MONTH |
| Manufacturer |
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Sanofi Aventis |
| Legal Classification |
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Rx
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| Pharmacological Class |
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GnRH analogue. |
| Generic Name |
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Leuprolide acetate 45mg per inj; ext-rel susp; for SC inj. |
| Also |
• ELIGARD 22.5mg 3-MONTH
• ELIGARD 30mg 4-MONTH
• ELIGARD 7.5mg 1-MONTH
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| Indications |
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Palliative treatment of advanced prostate cancer. |
| Children |
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See Contraindications. |
| Adults |
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Allow product to reach room temperature before using; inject within 30 minutes of mixing. Use correct formulation. 7.5mg SC once per month; or 22.5mg SC once every 3 months; or 30mg SC once every 4 months; or 45mg SC once every 6 months. Rotate inj site. |
| Contraindications |
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Women. Children. Pregnancy (Cat.X). |
| Precautions |
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May worsen metastatic vertebral lesions and/or urinary tract obstruction; monitor closely during first few weeks. Monitor serum testosterone, PSA. |
| Adverse Reactions |
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Hot flashes/sweats, testicular atrophy, gynecomastia, local reactions, asthenia, pain, spinal cord compression, decreased bone density; transient worsening of signs/symptoms (eg, bone pain, urinary tract obstruction, neuropathy, hematuria). |
| How Supplied |
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Single-use kit—1 |
| Additional Resources |
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• Related Prescribing Note |
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