Monograph Details
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Musculoskeletal Disorders
> Muscle spasms
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NORGESIC |
| Manufacturer |
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Graceway Pharmaceuticals |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Anticholinergic muscle relaxant (central) + salicylate. |
| Generic Name |
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Orphenadrine citrate 25mg, aspirin 385mg, caffeine 30mg; tabs. |
| Also |
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• NORGESIC FORTE
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| Indications |
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Painful musculoskeletal conditions. |
| Children |
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Not recommended. |
| Adults |
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1–2 tabs 3–4 times daily. |
| Contraindications |
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NSAID allergy. Varicella or influenza in teenagers. Glaucoma. Achalasia. GU or GI obstruction. Myasthenia gravis. |
| Precautions |
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Coronary disease, insufficiency or tachycardia. History of bronchospasm. Peptic ulcer. Coagulation disorders. Monitor blood pressure, BUN, uric acid levels. Pregnancy (Cat.C). Nursing mothers. |
| Interactions |
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Increased risk of GI bleed/ulcer with alcohol, aspirin, NSAIDs, corticosteroids, anticoagulants. Potentiates oral hypoglycemics, anticholinergics, protein-bound drugs (eg, warfarin). Antagonizes steroids, barbiturates, phenylbutazone, uricosurics. Tremor and mental confusion with propoxyphene. |
| Adverse Reactions |
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Tachycardia, transient dizziness or syncope, GI upset/bleed, anticholinergic effects (eg, dry mouth, blurred vision, increased intraocular pressure, urinary retention), weakness, headache, rash, blood dyscrasias. |
| How Supplied |
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Tabs—100 |
| Additional Resources |
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• Related Prescribing Note |
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