Monograph Details

Musculoskeletal Disorders > Muscle spasms
MESTINON
Manufacturer
Valeant Pharmaceuticals, Inc
Legal Classification
Rx
Pharmacological Class
Cholinesterase inhibitor.
Generic Name
Pyridostigmine bromide 60mg; scored tabs.
Also
MESTINON INJECTION
MESTINON SYRUP
MESTINON TIMESPAN
Indications
Myasthenia gravis.
Children
Not recommended.
Adults
Usually: 600mg daily in divided doses.
Contraindications
Intestinal or urinary obstruction.
Precautions
Bronchial asthma. Cardiac dysrhythmias (inj). Monitor for cholinergic and myasthenic crisis, differentiate and treat (see literature). Pregnancy. Nursing mothers.
Interactions
Reversal of nondepolarizing muscle relaxants. Antagonized by atropine.
Adverse Reactions
GI upset, increased salivation and bronchial secretions, miosis and diaphoresis, muscle cramps, fasciculation and weakness, thrombophlebitis (inj).
How Supplied
Tabs—100, 500
Syrup—pt
Timespan—100
Amp (2mL)—10
Additional Resources
Related Prescribing Note