Monograph Details
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Musculoskeletal Disorders
> Muscle spasms
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FEXMID |
| Manufacturer |
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Victory Pharma |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Muscle relaxant (central). |
| Generic Name |
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Cyclobenzaprine HCl 7.5mg, tabs. |
| Indications |
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Acute muscle spasms, as an adjunct to rest and physical therapy. |
| Children |
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<15yrs: not recommended. |
| Adults |
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≥15yrs: initially 5mg 3 times daily, may increase to 7.5mg or 10mg 3 times daily; max 2–3 weeks. Elderly or hepatic impairment: consider less frequent dosing. |
| Contraindications |
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During or within 14 days of MAOIs. Acute post-MI. Arrhythmias, heart block, other conduction disturbances. CHF. Hyperthyroidism. |
| Precautions |
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Hepatic impairment (if moderate to severe: not recommended). Urinary retention. Angle-closure glaucoma. Increased intraocular pressure. Elderly. Pregnancy (Cat.B). Nursing mothers. |
| Interactions |
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See Contraindications. Hypertensive crisis with MAOIs. Potentiates anticholinergics, alcohol, other CNS depressants. May antagonize guanethidine, clonidine. Tramadol increases seizure risk. |
| Adverse Reactions |
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Drowsiness, dry mouth, dizziness, fatigue, headache, GI upset, irritability, nervousness, asthenia, blurred vision, confusion. |
| How Supplied |
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Tabs—100 |
| Additional Resources |
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• Related Prescribing Note |
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