Monograph Details

Musculoskeletal Disorders > Muscle spasms
Baclofen
Manufacturer
Various generic manufacturers
Legal Classification
Rx
Pharmacological Class
Muscle relaxant (central).
Generic Name
Baclofen 10mg, 20mg; scored tabs.
Indications
Spasticity associated with MS and spinal cord injury or disease.
Children
Not recommended.
Adults
5mg 3 times daily. Increase in increments of 5mg 3 times daily every 3 days if needed; max 80mg daily. Use lowest dose possible.
Precautions
Impaired renal function. Beneficial spasticity. Stroke. Epilepsy. Avoid abrupt cessation. Pregnancy. Nursing mothers.
Interactions
Alcohol and other CNS depressants potentiated.
Adverse Reactions
Transient drowsiness, confusion, dizziness, weakness, fatigue, headache, hypotension, nausea, increased urinary frequency; seizures and hallucinations on abrupt withdrawal.
How Supplied
Tabs—contact supplier
Additional Resources
Related Prescribing Note