Monograph Details
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Musculoskeletal Disorders
> Arthritis/rheumatic disorders
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MOTRIN ORAL DROPS |
| Manufacturer |
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McNeil Consumer & Specialty Pharmaceuticals |
| Legal Classification |
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OTC |
| Pharmacological Class |
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NSAID (propionic acid deriv.). |
| Generic Name |
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Ibuprofen 40mg/mL; susp; berry flavor. |
| Also |
• MOTRIN CAPLETS
• MOTRIN SUSPENSION
• MOTRIN TABLETS
• MOTRIN CHEWABLE
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| Indications |
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Rheumatoid arthritis (RA). Osteoarthritis (OA). Juvenile arthritis (JRA). |
| Children |
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JRA: 30–40mg/kg per day in 3–4 doses. May use 20mg/kg per day in 3–4 doses for milder disease. |
| Adults |
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RA, OA: 400–800mg 3–4 times daily; max 3.2g/day. |
| Contraindications |
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Aspirin allergy. 3rd trimester pregnancy. Coronary artery bypass graft surgery. |
| Precautions |
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Advanced renal disease: not recommended. History of upper GI disease. Active peptic ulcer. Impaired renal or hepatic function. Edema. Hypertension. Cardiac failure. Bleeding disorders. Diabetes. Monitor blood, hepatic, renal, and ocular function in chronic use. Discontinue if visual or liver dysfunction occurs. Dehydration. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers: not recommended. |
| Interactions |
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Avoid aspirin. May increase bleeding with anticoagulants. Increases serum lithium levels. May increase toxicity of methotrexate. May decrease effect of furosemide, thiazide diuretics. Increased risk of GI bleed with alcohol. |
| Adverse Reactions |
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Peptic ulcer or perforation, GI bleeding, vision disorders, nausea, epigastric pain, heartburn, dizziness, rash (discontinue if occurs), edema, renal papillary necrosis, jaundice, hepatitis. See literature re: risk of cardiovascular events. |
| How Supplied |
Tablets—100, 500
Caplets—100
Chewable tablets—100
Susp—4oz, 16oz
Drops—15mL |
| Additional Resources |
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• Related Prescribing Note |
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