Monograph Details
|
|
Musculoskeletal Disorders
> Arthritis/rheumatic disorders
|
|
Choline magnesium trisalicylate |
| Manufacturer |
|
Various generic manufacturers |
| Legal Classification |
|
Rx
|
| Pharmacological Class |
|
Salicylate (non-acetylated). |
| Generic Name |
|
Salicylate (as choline magnesium trisalicylate) 500mg, 750mg, 1g; scored tabs. |
| Also |
|
• Choline magnesium trisalicylate liquid
|
| Indications |
|
Osteoarthritis. Rheumatoid arthritis. Painful shoulder. Juvenile rheumatoid arthritis, other conditions requiring antiinflammatory action in children. |
| Children |
|
<12kg: not recommended. 12–37kg: 50mg/kg/day. >37kg: 2.25g/day. Both in 2 divided doses. |
| Adults |
|
3g daily at bedtime or in 2 divided doses. Elderly:750mg three times daily. |
| Contraindications |
|
Varicella or influenza in children and teenagers. Pregnancy at term. |
| Precautions |
|
Renal dysfunction: monitor salicylate levels. Chronic renal failure. Erosive gastritis. Peptic ulcer. Elderly. Pregnancy (Cat.C). Labor & delivery, nursing mothers: not recommended. |
| Interactions |
|
May potentiate anticoagulants, hypoglycemics, methotrexate. Urinary alkalinizers, antacids, corticosteroids may reduce plasma salicylate levels; urinary acidifiers may increase salicylate plasma levels. May antagonize uricosurics and spironolactone. |
| Adverse Reactions |
|
Salicylism, tinnitus, hearing impairment, headache, dizziness, drowsiness, lethargy. |
| How Supplied |
|
Contact supplier |
| Additional Resources |
|
• Related Prescribing Note |
|
|
|
|
