Monograph Details
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Infections & Infestations
> Viral infections
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ZOVIRAX SUSPENSION |
| Manufacturer |
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GlaxoSmithKline Pharmaceuticals |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Nucleoside analogue. |
| Generic Name |
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Acyclovir 200mg/5mL; banana flavor. |
| Also |
• ZOVIRAX CAPSULES
• ZOVIRAX TABLETS
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| Indications |
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Genital herpes. Herpes zoster. Varicella. |
| Children |
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<2yrs: not recommended. ≥2yrs: Varicella (start at earliest sign/symptom): 20mg/kg 4 times daily for 5 days; max 800mg/dose. >40kg: as adult. Others: see literature. |
| Adults |
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May give with food. Genital herpes: Initially 200mg every 4 hrs (5 times daily) for 10 days. Chronic: 400mg 2 times daily or 200mg 3–5 times daily for up to 12 months, then reevaluate. Intermittent: (at 1st sign of recurrence) 200mg every 4 hrs (5 times daily) for 5 days. Herpes zoster: 800mg every 4 hrs (5 times daily) for 7–10 days. Varicella (start at earliest sign/symptom): 800mg 4 times daily for 5 days. Renal impairment: reduce dose (see literature); give another dose after hemodialysis. |
| Contraindications |
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Valacyclovir hypersensitivity. |
| Precautions |
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Renal impairment: see literature. Maintain adequate hydration. Pregnancy (Cat.B). Nursing mothers. |
| Interactions |
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Avoid nephrotoxic drugs. Potentiated by probenecid. |
| Adverse Reactions |
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Nausea, vomiting, headache, CNS disturbances (esp. elderly), diarrhea, vertigo, myalgia, rash, malaise, viral resistance, renal failure, thrombotic thrombocytopenic purpura/hemolytic uremic syndrome in immunocompromised patients. |
| How Supplied |
Caps, tabs—100
Susp—pt |
| Additional Resources |
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• Related Prescribing Note |
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