Monograph Details
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Infections & Infestations
> Tuberculosis
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RIFADIN IV INJECTION |
| Manufacturer |
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Sanofi Aventis |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Rifamycin. |
| Generic Name |
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Rifampin 600mg/vial. |
| Also |
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• RIFADIN
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| Indications |
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Susceptible pulmonary tuberculosis. |
| Children |
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10–20mg/kg/day; max 600mg. Oral give 1 hr before or 2 hrs after meals. Preparation of suspension: see literature. |
| Adults |
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600mg daily. Oral give 1 hr before or 2 hrs after meals. |
| Precautions |
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Use with other antituberculars. Impaired hepatic function. Monitor hepatic function and patients on intermittent therapy. Rifampin may stain body secretions and contact lenses. Pregnancy (Cat.C). Nursing mothers: not recommended. |
| Interactions |
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Reduces serum levels of protease inhibitors: avoid concomitant use. Antagonizes anticoagulants, cardiac glycosides, oral hypoglycemics, oral contraceptives, others (by inducing metabolic enzymes). Avoid use within 8 hours of PAS. Concomitant ketoconazole decreases serum concentration of both drugs. |
| Adverse Reactions |
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Hepatitis, jaundice, GI upset, headache, drowsiness, ataxia, dizziness, confusion, visual disturbances, muscular weakness, fever, urticaria, blood dyscrasias. |
| How Supplied |
150mg—30
300mg—30, 60, 100
Vials—1 |
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