Monograph Details
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Infections & Infestations
> Fungal infections
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GRIS-PEG |
| Manufacturer |
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Pedinol Pharmacal, Inc. |
| Legal Classification |
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Rx
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| Generic Name |
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Griseofulvin 125mg, 250mg; ultramicrosize; scored tabs. |
| Indications |
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Ringworm infections of the skin, scalp, and nails. |
| Children |
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<2 yrs: not recommended. 35-60lbs: 125–187.5mg daily. >60lbs: 187.5mg–375mg daily. |
| Adults |
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375mg daily as 1 or more divided doses; max 750mg daily. |
| Contraindications |
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Porphyria. Hepatocellular failure. Pregnancy. |
| Precautions |
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Continue therapy until infection is eradicated. Periodic monitoring of renal, hepatic, and hematopoietic functions. Discontinue if granulocytopenia occurs. Penicillin sensitivity. Avoid exposure to sunlight or UV light. Nursing mothers. |
| Interactions |
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Antagonizes oral anticoagulants. Antagonized by barbiturates. May potentiate alcohol. Oral contraceptives may be less effective. |
| Adverse Reactions |
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Oral thrush, GI distress, dizziness, confusion, peripheral neuritis, photosensitivity, granulocytopenia, leukopenia, proteinuria, lupus-like syndrome. |
| How Supplied |
Tabs 125mg—100
250mg—100, 500 |
| Additional Resources |
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• Related Prescribing Note |
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