Monograph Details
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Infections & Infestations
> Bacterial infections
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VANTIN |
| Manufacturer |
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Pfizer Labs |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Cephalosporin. |
| Generic Name |
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Cefpodoxime proxetil 100mg, 200mg; tabs. |
| Also |
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• VANTIN GRANULES
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| Indications |
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Susceptible mild to moderate infections including acute otitis media, acute bacterial exacerbations of chronic bronchitis, acute maxillary sinusitis, pharyngitis/tonsillitis, acute community-acquired pneumonia, urinary tract, skin and skin structures; cervical, anorectal (females only) and urethral gonorrhea. |
| Children |
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Use susp. <2 months: not recommended. 2months–12yrs: Acute otitis media: 5mg/kg (max 200mg) every 12 hrs for 5 days. Pharyngitis/tonsillitis: 5mg/kg (max 100mg) every 12 hrs for 5–10 days. Sinusitis: 5mg/kg (max 200mg) every 12 hrs for 10 days. |
| Adults |
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Take tabs with food. ≥13 yrs: Pneumonia: 200mg every 12 hours for 14 days. Bronchitis, sinusitis: 200mg every 12 hours for 10 days. Pharyngitis/tonsillitis: 100mg every 12 hours for 5–10 days. Skin and skin structures: 400mg every 12 hours for 7–14 days. UTI: 100mg every 12 hours for 7 days. Uncomplicated gonorrhea: 200mg once as a single dose. Renal failure or hemodialysis: see literature. |
| Precautions |
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Penicillin or other allergy. Labor & delivery. Pregnancy (Cat.B). Nursing mothers: not recommended. |
| Interactions |
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Antacids, H2 antagonists, oral anticholinergics may decrease efficacy. Potentiated by probenecid. Avoid concomitant diuretics, other nephrotoxic drugs. May cause false (+) direct Coomb's test. |
| Adverse Reactions |
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GI upset, abdominal pain, headache, rash, anaphylaxis. |
| How Supplied |
Tabs—20, 100
Susp—50mL, 75mL, 100mL |
| Additional Resources |
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• Related Prescribing Note |
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