Monograph Details
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Infections & Infestations
> Bacterial infections
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SUPRAX for ORAL SUSPENSION |
| Manufacturer |
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Lupin Pharmaceuticals, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Cephalosporin. |
| Generic Name |
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Cefixime 100mg/5mL, 200mg/5mL; strawberry flavor; pwd for reconstitution. |
| Also |
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• SUPRAX
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| Indications |
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Susceptible infections, including otitis media, pharyngitis, tonsillitis, acute bronchitis, acute exacerbation of chronic bronchitis; uncomplicated UTIs and cervical or urethral gonorrhea. |
| Children |
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<6 months: not recommended. <50kg and 6 months–12yrs: 8mg/kg once daily or 4mg/kg every 12 hrs. >50kg or >12yrs: use adult dose. Renal impairment: CrCl 21–59mL/min: reduce dose by ¼; CrCl<20mL/min or dialysis: reduce dose by ½. |
| Adults |
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400mg once daily or 200mg every 12 hrs. Gonorrhea: 400mg once. Renal impairment: CrCl 21–59mL/min: reduce dose by ¼; CrCl<20mL/min or dialysis: reduce dose by ½. |
| Precautions |
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Penicillin or other allergy. Renal impairment. History of GI disease. Labor and delivery. Pregnancy (Cat.B). Nursing mothers. |
| Interactions |
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May potentiate carbamazepine, anticoagulants (eg, warfarin) (monitor). May cause false (+) Clinitest, direct Coomb's, nitroprusside test for ketones. Potentiated by probenecid. |
| Adverse Reactions |
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GI upset, rash, drug fever, pruritus, headache, dizziness, transient renal and hepatic effects, seizures. |
| How Supplied |
Tabs—50, 100
Susp 100mg/5mL—50mL, 75mL, 100mL
200mg/5mL—25mL, 37.5mL, 50mL, 75mL, 100mL |
| Additional Resources |
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• Related Prescribing Note |
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