Monograph Details
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Infections & Infestations
> Bacterial infections
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OMNICEF for ORAL SUSPENSION |
| Manufacturer |
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Abbott Laboratories |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Cephalosporin. |
| Generic Name |
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Cefdinir 125mg/5mL, 250mg/5mL; pwd for reconstitution; strawberry-cream flavor. |
| Also |
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• OMNICEF
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| Indications |
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Susceptible mild-to-moderate infections, including community-acquired pneumonia, acute exacerbations of chronic bronchitis, acute maxillary sinusitis, pharyngitis/tonsillitis, uncomplicated skin and skin structure infections, acute otitis media. |
| Children |
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Use susp. <6months: not recommended. 6months–12yrs: Otitis media, pharyngitis/tonsillitis: 7mg/kg every 12hrs for 5–10 days, or 14mg/kg every 24hrs for 10 days. Sinusitis: 7mg/kg every 12hrs, or 14mg/kg every 24hrs, for 10 days. Skin and skin structure: 7mg/kg every 12hrs for 10 days. For all: max 600mg/day; see literature for chart. Renal insufficiency (CrCl <30mL/min per 1.73m2): 7mg/kg (max 300mg) once daily. Hemodialysis: give initial and subsequent doses at end of session (see literature). |
| Adults |
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Use caps. ≥13yrs: Pneumonia, skin and skin structure: 300mg every 12hrs for 10 days. Bronchitis, pharyngitis/tonsillitis: 300mg every 12hrs for 5–10 days, or 600mg every 24hrs for 10 days. Sinusitis: 300mg every 12hrs, or 600mg every 24hrs, for 10 days. Renal insufficiency (CrCl <30mL/min): 300mg once daily. Hemodialysis: 300mg (or 7mg/kg) at end of session then 300mg (or 7mg/kg) every other day. |
| Precautions |
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Penicillin or other allergy. Renal insufficiency. History of colitis. Labor & delivery. Pregnancy (Cat.B). |
| Interactions |
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Antagonized by magnesium- or aluminum-containing antacids or iron supplements (except iron-fortified infant formulas): separate dosing by 2hrs. Potentiated by probenecid. May cause false (+) glucose test with Clinitest, Fehling's or Benedict's soln, or direct Coomb's test. |
| Adverse Reactions |
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GI disturbances, abdominal pain, headache, rash. |
| How Supplied |
Caps—60
Omni-Pac (10 x 300mg caps)—3
Susp—60mL, 100mL |
| Additional Resources |
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• Related Prescribing Note |
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