Monograph Details
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Infections & Infestations
> Bacterial infections
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KEFLEX |
| Manufacturer |
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MiddleBrook Pharmaceuticals |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Cephalosporin. |
| Generic Name |
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Cephalexin 250mg, 333mg, 500mg, 750mg; caps. |
| Indications |
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Susceptible infections including otitis media, skin and skin structure, bone, respiratory or genitourinary tract. |
| Children |
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25–50mg/kg per day in divided doses; max 100mg/kg per day. Otitis media: 75–100mg/kg per day in 4 divided doses. Strep pharyngitis (>1 year of age) or skin and skin structure: may give in 2 divided doses every 12 hours. |
| Adults |
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1–4g/day in divided doses. Usual dose: 250mg every 6 hours. Strep pharyngitis, skin and skin structure, and uncomplicated cystitis (>15 years of age): 500mg every 12 hours. Treat cystitis for 7–14 days. Max 4g/day. |
| Precautions |
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Penicillin or other allergy. Severe renal dysfunction. GI disease (esp. colitis). Discontinue if colitis occurs and treat. Pregnancy (Cat.B). Nursing mothers. |
| Interactions |
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Potentiates metformin (monitor and adjust metformin dose). Potentiated by probenecid. May cause false (+) Coomb's test or glucose test with Clinitest or Benedict's or Fehling's soln. |
| Adverse Reactions |
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Diarrhea, other GI disturbances, dizziness, fatigue, headache, hypersensitivity reactions, itch; rare: blood dyscrasias, elevated liver enzymes. |
| How Supplied |
Caps 250mg, 500mg—20, 100
333mg—(available soon)
750mg—50 |
| Additional Resources |
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• Related Prescribing Note |
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