Monograph Details
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Infections & Infestations
> Bacterial infections
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DISPERMOX |
| Manufacturer |
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Ranbaxy Pharmaceuticals, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Broad-spectrum penicillin. |
| Generic Name |
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Amoxicillin (as trihydrate) 200mg, 400mg, 600mg; tabs for oral susp; strawberry-flavor; contains phenylalanine. |
| Indications |
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Susceptible infections including ear/nose/throat (ENT), lower respiratory tract, skin and skin structure, genitourinary tract, acute uncomplicated gonorrhea. |
| Children |
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Do not chew or swallow tablets; mix with 2 teaspoonsful of water and drink entire mixture immediately. Do not subdivide doses (use 200mg tab only for a 200mg dose, and 400mg tab only for a 400mg dose, and 600mg tab only for a 600mg dose). Neonates and infants ≤3months: max 30mg/kg per day in divided doses every 12 hrs. >3months: Mild to moderate ENT, skin, or genitourinary: 25mg/kg per day in divided doses every 12hrs or, 20mg/kg per day in divided doses every 8hrs. Lower respiratory or severe ENT, skin, or genitourinary: 45mg/kg per day in divided doses every 12hrs or, 40mg/kg per day in divided doses every 8hrs. Gonorrhea: ≤2yrs: not recommended; >2yrs: 50mg/kg with 25mg/kg probenecid once. >40kg: use other forms. Renal dysfunction (CrCl <30mL/min): <12 yrs: not recommended; ≥12yrs: reduce dose, see literature. |
| Adults |
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Use other forms. |
| Precautions |
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Cephalosporin, imipenem, or other allergy: not recommended. Monitor blood, renal, and hepatic function in long-term use. Pregnancy (Cat.B). Nursing mothers. |
| Interactions |
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May cause false (+) glucose test with Clinitest, Benedict's or Fehling's soln. Serum levels increased by probenecid. |
| Adverse Reactions |
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GI upset, hypersensitivity reactions (eg, urticaria, rash, Stevens-Johnson syndrome, anaphylaxis), hyperactivity, blood dyscrasias. |
| How Supplied |
Tabs 200mg—20, 60, 1000
400mg—20, 60, 500
600mg—20, 60, 100 |
| Additional Resources |
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• Related Prescribing Note |
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