Monograph Details
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Infections & Infestations
> Bacterial infections
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CLEOCIN INJECTION |
| Manufacturer |
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Pfizer Labs |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Lincosamide. |
| Generic Name |
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Clindamycin (as phosphate) 150mg/mL; contains benzyl alcohol. |
| Also |
• CLEOCIN
• CLEOCIN PEDIATRIC GRANULES
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| Indications |
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Serious susceptible infections where less toxic antibiotics are inappropriate, including respiratory, skin and soft tissue, septicemia, intraabdominal, female pelvic or genital; bone and joint (inj). |
| Children |
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Neonates: 15–20mg/kg per day. >1 month: 20–40mg/kg per day IM or IV. Both: give in 3–4 equally divided doses. Or: serious infections: 350mg/m2 per day; more severe: 400mg/m2 per day. |
| Adults |
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Serious: 0.6–1.2g daily. More severe: 1.2–2.7g/day IM or IV. Both: give in 2–4 equally divided doses; max 600mg per IM inj and 4.8g/day. |
| Precautions |
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Not for treatment of meningitis. Discontinue if colitis occurs and treat. Monitor neonates. Allergy. Asthma (75mg, 150mg caps). GI disease (esp. colitis). Monitor blood, renal, and hepatic function in long-term use and in children. Renal or hepatic disease with metabolic aberrations. Pregnancy (Cat.B). Nursing mothers. |
| Interactions |
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May potentiate neuromuscular blocking agents. May antagonize erythromycin. Antiperistaltic agents may worsen colitis. |
| Adverse Reactions |
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Pseudomembranous colitis, diarrhea, GI upset, rash, anaphylaxis, jaundice, renal dysfunction, blood dyscrasias, polyarthritis. |
| How Supplied |
Caps 75mg—100
150mg, 300mg—16, 100
Granules (100mL)—1
Inj (2mL, 4mL vials)—25 |
| Additional Resources |
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• Related Prescribing Note |
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