Monograph Details
|
|
Infections & Infestations
> Bacterial infections
|
|
CEFZIL |
| Manufacturer |
|
Bristol-Myers Squibb |
| Legal Classification |
|
Rx
|
| Pharmacological Class |
|
Cephalosporin. |
| Generic Name |
|
Cefprozil 250mg, 500mg; tabs. |
| Also |
|
• CEFZIL ORAL SUSPENSION
|
| Indications |
|
Susceptible mild to moderate infections, including pharyngitis/tonsillitis, secondary bacterial infection of acute bronchitis, acute bacterial exacerbation of chronic bronchitis, acute sinusitis, skin and skin structure, otitis media. |
| Children |
|
Otitis media: <6months: not recommended; 6months to 12yrs: 15mg/kg every 12 hrs. Acute sinusitis: <6months: not recommended; 6months to 12yrs: 7.5mg/kg (mild) or 15mg/kg (moderate to severe) every 12 hrs. Pharyngitis/tonsillitis: <2yrs: not recommended; 2–12yrs: 7.5mg/kg every 12 hrs. Skin and skin structure: <2yrs: not recommended; 2–12yrs: 20mg/kg every 24 hrs. All: for 10 days. |
| Adults |
|
≥13yrs: Pharyngitis/tonsillitis: 500mg every 24 hrs. Acute sinusitis: 250mg (mild) or 500mg (moderate to severe) every 12 hrs. Bronchitis: 500mg every 12 hrs. Skin and skin structure: 250mg every 12 hrs or 500mg every 12–24 hrs. All: for 10 days. CrCL<30mL/min: 50% of standard dose. |
| Precautions |
|
Penicillin or other allergy. Renal impairment, reduce dose. Monitor renal function. GI disease (esp. colitis). Labor & delivery. Pregnancy (Cat.B). Nursing mothers. |
| Interactions |
|
Avoid diuretics, other nephrotoxic drugs, including aminoglycosides. Potentiated by probenecid. May cause false (+) Clinitest. |
| Adverse Reactions |
|
GI upset, elevated liver enzymes, dizziness. |
| How Supplied |
Tabs 250mg—100
500mg—50, 100
Susp—50mL, 75mL, 100mL |
| Additional Resources |
|
• Related Prescribing Note |
|
|
|
|
