Monograph Details
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Infections & Infestations
> Bacterial infections
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CEFTIN ORAL SUSPENSION |
| Manufacturer |
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GlaxoSmithKline Pharmaceuticals |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Cephalosporin. |
| Generic Name |
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Cefuroxime (as axetil) 125mg/5mL, 250mg/5mL; pwd for reconstitution; contains phenylalanine; tutti-frutti flavor. |
| Also |
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• CEFTIN
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| Indications |
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Susceptible infections including pharyngitis/tonsillitis, otitis media, impetigo, acute maxillary sinusitis. |
| Children |
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Give with food. <3 months: not recommended. 3 months–12 years: Pharyngitis/tonsillitis: 20mg/kg per day in 2 divided doses for 10 days; max 500mg/day. Otitis media, impetigo, sinusitis: 30mg/kg per day in 2 divided doses for 10 days; max 1g/day. |
| Adults |
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Not applicable. |
| Precautions |
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Tabs and susp not bioequivalent; do not interchange on a mg/mg basis. Penicillin or other allergy. History of colitis; discontinue if colitis occurs and treat. Renal impairment. Monitor prothrombin time in renal or hepatic dysfunction, stabilized on anticoagulant, poor nutritional state, or long-term use. Labor & delivery. Pregnancy (Cat.B). Nursing mothers: consider discontinuing nursing during treatment. |
| Interactions |
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May cause false (+) Fehling's or Benedict's soln, Clinitest, or Coomb's test. Antacids, others that decrease gastric acidity may inhibit absorption. Potentiated by probenecid. Caution with potent diuretics, other nephrotoxic drugs. |
| Adverse Reactions |
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GI disturbances, transient increase of AST, ALT, LDH, eosinophilia, bitter taste; convulsions (overdose). |
| How Supplied |
Tabs—20, 60
Susp 125mg/5mL—100mL
Susp 250mg/5mL—50mL, 100mL |
| Additional Resources |
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• Related Prescribing Note |
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