Monograph Details
|
|
Infections & Infestations
> Bacterial infections
|
|
BICILLIN L-A |
| Manufacturer |
|
King Pharmaceuticals, Inc. |
| Legal Classification |
|
Rx
|
| Pharmacological Class |
|
Penicillinase-sensitive penicillin. |
| Generic Name |
|
Penicillin G benzathine 600,000 units/mL; susp for deep IM inj; contains parabens. |
| Indications |
|
Susceptible infections, including mild to moderate upper respiratory strep infections, syphilis. Follow-up prophylaxis of rheumatic heart disease, acute glomerulonephritis. |
| Children |
|
Give by deep IM inj into upper outer quadrant of buttock or midlateral thigh; rotate inj sites. Upper respiratory Group A strep (<60 lbs): 300,000 to 600,000 units once; (>60 lbs): 900,000 units once. Congenital syphilis (<2 years): 50,000 units/kg once; (≥2 years): individualize. |
| Adults |
|
Give by deep IM inj into upper outer quadrant of buttock; rotate inj sites. Upper respiratory Group A strep: 1.2 million units once. Syphilis (primary, secondary, latent): 2.4 million units once; (tertiary and neurosyphilis): 2.4 million units every 7 days for 3 doses. Rheumatic heart disease, acute glomerulonephritis: 1.2 million units once per month, or 600,000 units every 2 weeks. |
| Contraindications |
|
Avoid intraarterial, intravascular, or intraneural injection. |
| Precautions |
|
Cephalosporin, imipenem, or other allergy: not recommended. Asthma. Monitor renal and hematopoietic function in prolonged use. Pregnancy (Cat.B). Nursing mothers. |
| Interactions |
|
Potentiated by probenecid. May cause false (+) glucose test with Clinitest. |
| Adverse Reactions |
|
Rash, serum sickness, anaphylaxis, blood dyscrasias, neuropathy, nephropathy, inj site reactions. |
| How Supplied |
Tubex 600,000 or 1.2 million units/syr (1 mL, 2 mL)—10 (w. 1 or 1.25 inch needles)
Disposable syringe 2.4million units/syr (4 mL)—10 (w. 2 inch needles) |
| Additional Resources |
|
• Related Prescribing Note |
|
|
|
|
