Monograph Details
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Infections & Infestations
> Bacterial infections
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BICILLIN C-R 900/300 |
| Manufacturer |
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King Pharmaceuticals, Inc. |
| Legal Classification |
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Rx
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| Pharmacological Class |
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Penicillinase-sensitive penicillin. |
| Generic Name |
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Penicillin G benzathine 900,000 units, penicillin G procaine 300,000 units; per syringe; susp for deep IM inj; contains parabens. |
| Also |
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• BICILLIN C-R
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| Indications |
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Susceptible moderately severe infections including respiratory, skin and soft tissue, erysipelas, scarlet fever, otitis media. |
| Children |
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Give by deep IM inj into midlateral thigh or buttock. Group A strep: one inj of 900/300 once. Pneumococcal: one inj of 900/300 every 2–3 days until afebrile for 48 hours. |
| Adults |
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Use other strengths. |
| Contraindications |
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Avoid intraarterial, intravascular, and intraneural inj. |
| Precautions |
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Cephalosporin, imipenem, or other allergy: not recommended. Asthma. Monitor renal and hematopoietic function in prolonged use. Pregnancy (Cat.B). Nursing mothers. |
| Interactions |
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Potentiated by probenecid. May cause false (+) glucose test with Clinitest. |
| Adverse Reactions |
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Rash, drug fever, serum sickness, anaphylaxis, blood dyscrasias, neuropathy, nephropathy, inj site reactions. |
| How Supplied |
C–R Tubex 600,000 units/mL (1mL, 2mL)—10 (w. 1 inch or 1.25 inch needles)
C–R disposable syringe 600,000 units/mL (4mL)—10 (w. 2 inch needles)
C–R 900/300 Tubex 1.2 million units/syringe (2mL)—10 (w. 1 inch or 1.25 inch needles) |
| Additional Resources |
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• Related Prescribing Note |
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